A Newly Developed Drug to Reduce Appetite for Weight Loss


Are you looking for a new drug to help you lose weight? Have you tried various weight loss pills, but they seem to just give you harmful side-effects instead of helping you shed those excess pounds? A new drug tested on mice may just be the solution to your weight loss problems.

Various drugs have been developed to aid in weight loss; however, not all of these focus on the real problem in weight gaining. Most weight loss pills focus on producing diarrhea to reduce the water and fat composition of the body; thereby producing weight loss effects. Since water is an important component of the human body, dehydration may lead to potential life-threatening incidences such as hypovolemia and electrolyte imbalances.

In a recent study published in the journal Cell Metabolism, a new drug has been formulated to aid in weight loss. This drug, which is JD5037, had been tested on mice and yielded desirable results in weight loss.

How Does the Drug Work?

The drug JD5037 increases the sensitivity to leptin, an appetite suppressant hormone. Leptin production is regulated by the brain and any increase in the levels will result in a loss of appetite. When the drug was administered to mice, they had significant appetite suppression, which resulted in weight loss.

The new drug has been seen to promote weight loss as well as maintain it. The problem with most weight loss pills is that they produce quick weight loss results, but lack the ability to maintain a healthy weight on a long-term basis. As a result of this, many people who want to lose weight return to their previous weight, or even gain some more. The advantage of JD5037 is it maintains a steady decline in appetite to reduce total calorie intake.

What are the Side-effects of the Drug?

There are no potential harmful side-effects of the drug because as the person has a reduced appetite, it also increases satiety levels wherein the person feels full even after eating a little. This prevents possible food starvation and food cravings because the person is indeed, satisfied with the small food intake.

However, some experts believe that this drug may lead to leptin desensitization in the long run, which means that the person taking the drug may no longer respond to it; thereby reducing its efficacy as the period of time over which the drug is taken increases.

Experts say that the real answer to weight loss needs is a balance between exercise and diet. Since the new drug focuses on decreasing the food intake, then, food reduction or a healthy diet may be the answer to weight loss needs even without special drugs.

Although the study was conducted in mice, people may benefit too because of the presence of natural leptin in humans. Nevertheless, future research should still be conducted to evaluate the efficacy of the drug in humans and to devise ways to reduce the leptin desensitization that can arise.

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